Filter and Sampling Rate Optimization for PPG-Based Detection of Autonomic Dysfunction: An ECG-guided Approach

Authors

  • Yi-Hui Kao Department of Medical Education and Research, National Taiwan University Hospital Yun-Lin Branch, Taiwan; Graduate Institute of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan
  • ِDanyal Shahmirzadi Graduate School of Engineering Science and Technology, National Yunlin University of Science and Technology, Douliou, Taiwan https://orcid.org/0009-0000-0180-0729
  • Sung-Tsang Hsieh Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan; Department of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei, Taiwan; Center of Precision Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan; Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine, Taipei, Taiwan
  • Wen-Fong Wang National Yunlin University of Science and Technology, Yunlin, Taiwan

DOI:

https://doi.org/10.2478/msr-2025-0024

Keywords:

photoplethysmography, electrocardiography, healthcare, wearable, autonomous, neuropathy

Abstract

Photoplethysmography (PPG) is well suited for wearable health applications, but has a lower frequency spectrum than electrocardiography (ECG) and is more affected by motion artifacts. In this study, ten signal filters from three categories were investigated in combination with different sampling rates to evaluate their effects on PPG signal quality. A correlation and accuracy analysis was performed comparing the interbeat intervals detected in PPG and ECG using Pearson correlation and absolute error. The results showed that specific filters with sampling rates as low as 40 Hz perform well in detecting autonomic neuropathy. The results highlight the potential of PPG with optimized filters and sampling rates for clinical screening of the autonomic nervous system (ANS) in wearable health monitoring.

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Published

01.10.2025

How to Cite

Filter and Sampling Rate Optimization for PPG-Based Detection of Autonomic Dysfunction: An ECG-guided Approach. (2025). Measurement Science Review, 25(4), 200-211. https://doi.org/10.2478/msr-2025-0024

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